No abstract

Epilepsy is more common in children than in any other age group apart from the geriatric population. Indeed epileptic seizures are more likely to occur on the first day of life than at any other time. The impact of epilepsy on every aspect of both the lives of the child and family is significant. Issues such as mental retardation, subtle neuropsychologic disturbances, cognitive problems, behavioral problems and learning difficulties are major factors affecting the children with epilepsy. The rate of new-onset seizures and epilepsy thereafter falls steeply but remains high throughout infancy, dropping further during childhood and into adolescence. Drug treatment forms one of the most important forms of therapy for a vast majority of epilepsy patients. The majority of patients can achieve complete seizure control by taking antiepileptic drugs (AEDs). AEDs can effectively control seizures in 70-80% of children with epilepsy. Antiepileptic drugs can be effective, but like all drugs acting on the CNS, cause side effects. AEDs do not 'cure' epilepsy; there is no evidence that they can influence the prognosis of the epilepsy. The decision to prescribe AEDs should be shared with the patient, who should be provided with information about the drug (including indications, side effects and licence status) and information about the condition including risks of not taking medication.

The main objective of the present study is to investigate the antioxidant activity of Tamra Bhasma and Tamra Yoga. 2,2 -Diphenyl-1-Picrylhydrazyl (DPPH) scavenging assay has been used in the determination of In Vitro antioxidant activity. Increasing order of Percentage of Inhibition was seen in 100 µl, 200 µl, 300 µl, 400 µl and 500 µl sample concentrations in both Tamra Bhasma and Tamra Yoga. Tamra Bhasma showed 58.67% of inhibition and Tamra Yoga showed 55.47% of inhibition in 500 µl sample concentrations respectively. The present study revealed that both the Tamra Bhasma and Tamra yoga showed good antioxidant activity. Tamra Bhasma showed relatively higher antioxidant activity when compared to Tamra Yoga.