Abstrak Ginjal kronik merupakan penyakit yang terjadi karena penurunan fungsi ginjal yang progresif dan menyebabkan kerusakan ginjal atau gagal ginjal. Penelitian ini bertujuan untuk melakukan analisis dan melakukan evaluasi terhadap kesesuaian penggunaan dosis obat pada pasien penderita penyakit ginjal kronis pada stage 3 hingga end stage renal disease berdasarkan dengan derajat keparahan ginjal yang dialami oleh pasien. Jenis penilitian ini adalah penelitian non eksperimental dengan pengumpulan data secara online menggunakan google formulir yang kemudian akan dilakukan pengolahan data dengan rancangan deskriptif. Pengambilan data dilakukan berdasarkan dengan kriteria inklusi yaitu pasien dengan penyakit ginjal kronis pada stage 3 hingga end stage renal disease dengan atau tanpa penyakit komorbid, memiliki data hasil tes laboratorium berupa nilai serum kreatinin , mengisi data penggunaan obat rutin dengan lengkap. Total responden yang memenuki kriteria tersebut sebanyak 42 pasien dengan rentang usia 15 sampai 84 tahun serta mengonsumsi obat secara rutin. Sampel yang didapatkan kemudian dianalisis secara deskriptif penggunaan dosis obat, frekuensi pemberian, dosis obat yang digunakan pasien akan berdasarkan dengan perhitungan glomerular filtration rate (GFR) yang dilakukan dengan menggunakan data nilai serum kreatinin, usia, dan jenis kelamin pada masing-masing pasien. Analisis hasil penelitian diperoleh bahwa dari 42 terdapat 19 pasien (45%) mendapatkan terapi obat yang memenuhi kesesuaian dosis seharusnya dan 23 pasien (55%) mendapatkan terapi obat yang tidak memenuhi kesesuaian dosis. Kata Kunci : Dosis Obat, GFR, Kesesuaian Dosis, Penyakit Ginjal Kronis. Abstract Chronic kidney is a disease that occurs due to a progressive decline in kidney function and causes kidney damage or kidney failure. This study aims to analyze and evaluate in appropriate for use of drug doses in patients with chronic kidney disease at stage 3 to end stage renal disease based on the degree of kidney severity experienced by the patient. This type of research is nonexperimental research by collecting data online using a google form which will then be processed with a descriptive design. Data were collected based on inclusion criteria, for patients with chronic kidney disease at stage 3 to end stage renal disease with or without comorbid disease, having laboratory test results data in the form of serum creatinine values, filling in complete data on routine drug use. The total number of respondents who met these criteria were 42 patients ranging in age from 15 to 84 years and who consumed drugs regularly. The sample obtained is then analyzed descriptively using drug dosage, frequency of administration, drug dose used by the patient will be based on the calculation of the glomerular filtration rate (GFR) which is carried out using data on the serum creatinine value, age, and sex in each patient. The analysis of the results showed that out of 42 there were 19 patients (45%) who received drug therapy that fulfilled the appropriate dosage and 23 patients (55%) received drug therapy that did not meet the dosage suitability. Keywords : Chronic Kidney Disease, Drug Dosage, Dosage Suitability, GFR.
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