This Article reports an investigation on the use of magnesium hydroxide nanoparticles dispersed in alcohols to inhibit two different and synergistic degradation processes usually affecting historically valuable manuscripts and, more generally, paper documents. We show that the preservation of paper from acid hydrolysis and oxidative ink corrosion can be achieved by stabilizing the final pH of deacidified paper around 6.5 to 7.5. Reactive magnesium hydroxide nanoparticles with a narrow size distribution, obtained by using a novel synthetic procedure, are very efficient in controlling paper's pH to avoid further degradation of cellulose from acid hydrolysis, oxidative ink corrosion, or both. The deacidification and antioxidant actions of magnesium hydroxide nanoparticles are compared with magnesium oxide particles present in one of the best mass deacidification methods (Bookkeeper).

No abstract

No abstract

No abstract

Biomaterials, once inserted in the oral cavity, become immediately covered by a layer of adsorbed proteins that consists mostly of salivary proteins but also of plasma proteins if the biomaterial is placed close to the gingival margin or if it becomes implanted into tissue and bone. It is often this protein layer, rather than the pristine biomaterial surface, that is subsequently encountered by colonizing bacteria or attaching tissue cells. Thus, to study this important initial protein adsorption from human saliva and serum and how it might be influenced through chemical modification of the biomaterial surface, we have measured the amount of protein adsorbed and analyzed the composition of the adsorbed protein layer using gel electrophoresis and western blotting. Here, we have developed an in vitro model system based on silica surfaces, chemically modified with 7 silane-based self-assembled monolayers that span a broad range of physicochemical properties, from hydrophilic to hydrophobic surfaces (water contact angles from 15° to 115°), low to high surface free energy (12 to 57 mN/m), and negative to positive surface charge (zeta potentials from –120 to +40 mV at physiologic pH). We found that the chemical surface functionalities exerted a substantial effect on the total amounts of proteins adsorbed; however, no linear correlation of the adsorbed amounts with the physicochemical surface parameters was observed. Only the adsorption behavior of a few singular protein components, from which physicochemical data are available, seems to follow physicochemical expectations. Examples are albumin in serum and lysozyme in saliva; in both, adsorption was favored on countercharged surfaces. We conclude from these findings that in complex biofluids such as saliva and serum, adsorption behavior is dominated by the overall protein-binding capacity of the surface rather than by specific physicochemical interactions of single protein entities with the surface.