Objective:
Identify from which PWV value, there is a greater possibility of identifying association with the presence of left ventricular hypertrophy (LVH), increased intima-media thickness (IMT) and presence of carotid plaque in hypertensive patients.
Design and method:
This is a cross-sectional study of 119 patients. ROC curves were performed for each cardiovascular biomarker. The analyses were performed considering the significance level of 0.05.
Results:
ROC curves were performed for each cardiovascular biomarker and the PWV values of 8.1m/s for LVH, 8.2m/s for increased IMT and 8.7 for the presence of carotid plaque were found, respectively. The PWV value of 8.2m/s identified the best parameter to find the three TOD outcomes. PWV above 8.2ms was associated with increased IMT (p = 0.004), with the presence of carotid plaque (p = 0.003) and with LVH (p<0.001). PWV above 8.2 showed greater sensitivity for IMT (AUC = 0.678, sensitivity 62.2), LVH (AUC = 0.717, sensitivity 87.2) and presence of plaque (AUC = 0.649, sensitivity 74.51) in the ROC curve.
Conclusions:
The 8.2m/s value is more sensitive in identifying the existence of cardiovascular biomarkers prematurely.
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