Catalytic, diastereoselective, and site-selective sp3 C–H hydroxylation and alkoxylation protocols featuring lactams that bear vicinal stereocenters, is described.
A functional group-tolerant and transition metal-free coupling of novel N,O- and N,S-heterocyclic vinyl chlorides, which affords fully carbosubstituted dihydro-1,4-oxazines/thiazines as well as bicyclic morpholines, is described.
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