The need for a basic epidemiological study, according to international standards, of the prevalence of IBD in Slovakia was increased by the dissolution of Czechoslovakia. This paper presents the results of CD prevalence to 30 April 1994 in Slovakia. To evaluate the statistical data of the prevalence of the disease according to age, sex, regions and districts, the authors employed the multi-dimensional Kruskal-Wallis test and cluster analysis and determined that the prevalence of CD in Slovakia is 6.75/100.000 inhabitants. The distribution differences indicate the need for further investigations of environmental differences. The socio-economic and psychological evaluation of the patients examined revealed some interesting associations. The psychological reaction to the disease is neurotic and depressive and a higher occurrence of affective symptomatology was observed in patients with permanent partnership and with children. On the other hand, the educational level and knowledge concerning the disease on the part of the patient had a positive influence on the reaction to the disease.