Landslide susceptibility mapping of the city of Da Lat, which is located in the landslide prone area of Lam Dong province of Central Vietnam region, was carried out using GIS based frequency ratio (FR) method. There are number of methods available but FR method is simple and widely used method for landslide susceptibility mapping. In the present study, eight topographical and geo-environmental landslide-conditioning factors were used including slope, elevation, land use, weathering crust, soil, lithology, distance to geology features, and stream density in conjunction with 70 past landslide locations. The results show that 6.27% of the area is in the very low susceptibility area, 21.03% in the low susceptibility area, 27.09% in the moderate susceptibility area and 27.41% of the area is in the high susceptibility zone and 18.21% in the very high susceptibility zone. The landslide susceptibility map produced in this study helps to assist decision makers in proper land use management and planning.

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Ovarian cancer is one of the most common gynecological malignancies. The gene RAD51involves homologous recombinational repair for double-strand breaks of DNA, so its polymorphisms and mutations are associated with cancer risk. The authors studied, by using a case-control design, whether single nucleotide polymorphism rs1801321 of RAD51 gene associated with ovarian cancer risk among Vietnamese females. Sample sets included 380 ovarian cancer cases and 380 healthy controls of similar age distribution. The genotypes of rs1801321 polymorphism were determined using the Polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) technique. The distribution of genotype GG, GT, TT was 55.3, 29.2, 15.5% for the patients group and 47.9, 41.8, 10.3% for the control group, respectively (p=0.001). The RAD51 rs1801321 polymorphism was associated with the risk of ovarian cancer among Vietnamese females.

The single nucleotide polymorphisms of the XRCC3 gene including rs1799794 affect the DNA double-strand break/repair. Therefore, it plays a critical part in the initiation of carcinogenesis. This study aimed to investigate the distribution of rs1799794 and the association between rs1799794 and breast cancer risk. The study was performed in 208 Vietnamese females suffering from breast cancer and 208 age-matched normal healthy controls. DNA was extracted from whole blood whilst genotyping was conducted using PCR-RFLP. The results show that the frequency of the A and G allele in the case group are 0.575 and 0.425, in the control group are 0.548 and 0.452. The frequency of AA, AG, GG genotype in the case group are 34.6, 45.7, and 19.7%; in the control group are 33.2, 43.3, and 23.5%. AG genotype of rs1799794 associated with disease onset early of breast cancer, increasing the risk of breast cancer among those who were 45 years old and younger. The GG genotype has protective effects and reduces the risk of breast cancer in the age group ≤45 years.