Gastrointestinal stromal tumours (GIST) are mesenchymal tumours that arise most commonly from the stomach. They are the 3 rd most common tumour diagnosed behind adenocarcinomas and lymphomas. The majority of these tumours are asymptomatic and incidentally diagnosed in UGI scopy or contrast enhanced CT abdomen and pelvis studies. Obstruction, ulceration, gastrointestinal (GI) haemorrhage and perforation warrants an urgent surgical intervention. GIST is medically managed by tyrosine kinase inhibitors and surgically by resection and anastomosis. This case report highlights the diagnosis and management of a 42-year-old gentleman who presented with vague right iliac fossa mass. Informed consent was obtained from the patient for publication of this case. This case was chosen to be reported because of the rare incidence of small intestine GIST in South India and the effectiveness of minimally invasive laparoscopic surgery in management.
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