Investigations were suggestive of severe macrocytic hypochromic anaemia (Hb 6.4 gm%), RBC 2.48 mill/cmm, Mean corpuscular volume (MCV) 82 fl, Packed cell volume (PCV) 22.6%, Mean corpuscular hemoglobin (MCH) 26 pg, Mean corpuscular hemoglobin concentration (MCHC) 28.4%, Red blood cell distribution width (RDW) 26% with peripheral smear showing hypochromic macrocytic picture. Her serum calcium value was low (9.4 mg/dl), while Serum B12, Random Blood Sugar (RBS), serum TSH (Thyroid ABSTRACT Infantile tremor syndrome (ITS) is a clinical entity characterized by tremors, skin pigmentation, anemia, developmental and mental retardation. It is most commonly found in Indian subcontinent and in children who are exclusively on breast feeding of vegetarian mother. Amongst all the etiological theories, nutritional theory is the most accepted one. Management of ITS is largely empirical and includes therapy of nutritional deficiency, anemia & tremors apart from appropriate care. Treatment of nutritional deficiency includes vitamin B12, multivitamins, folic acid, iron, calcium, zinc, magnesium and high protein diet. In this article, three cases of ITS with classical picture have been reported.

<p>Ondansetron is an antiemetic drug that belongs to 5-hydroxytryptamine (5-HT₃) receptor antagonists group. It has been widely used to treat nausea and vomiting due to chemotherapy, post surgery or due to any other gastrointestinal problem with 5-HT₃ receptors involvement. The typical adverse drug reactions of Ondansetron include headache, dizziness, constipation or diarrhoea. Here, we have observed the skin reaction around the site of injection following Ondansetron administration. Recognition of this hypersensitivity reaction may allow better preparedness of clinicians to manage this condition.</p>

The has become the most critical health problem worldwide. It was first started from Wuhan, China and now it has affected more than 230 countries and millions of people. The diabetic patients with uncontrolled glycemic state for long term can result in many microvascular and macrovascular complications. Hence they are most commonly affected individuals during COVID-19. In this review we have briefed about the impact of COVID-19 in diabetes, the different pathophysioloy and management of diabetes in this phase.