Chemo-cycles of doxorubicin-nanocarriers are reported to be highly indicative of cell deformations and are a progressive indicator of acquired drug resistance.
New ferrocenylphosphinoimidazolidines containing central chirality and planar chirality were found to act as highly effective chiral ligands in Pd-catalyzed asymmetric allylic alkylation of 1,3-diphenyl-2-propenyl acetate with dimethyl malonate.
Compounds (V) show strong activity against Gram positive bacteria comparable to that of linezolid and eperezolid. (VIIb) and (VIIc) shows superior antibacterial activity against Gram-negative Klebsiella. -(LOHRAY*, B. B.; LOHRAY, V. B.; SRIVASTAVA, B. K.; GUPTA, S.; SOLANKI, M.; KAPADNIS, P.; TAKALE, V.; PANDYA, P.; Bioorg. Med. Chem.
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