Sentinel lymph node biopsy is the widely acceptable method for the examination of the breast cancer in the patients. This biopsy is considered as the best method for identifying the axillary involvement. Various dyes are used in this biopsy to find the sentinel lymph node. However, methylene blue dye (MBD) is considered to have a low risk of anaphylaxis, be cost effective and widely available.A systematic review and meta-analysis is performed on the utilisation of the methylene blue dye in the sentinel lymph node biopsy in the examination of breast cancer.Eight studies were appropriate for the inclusion criteria that were analysed systematically wherein meta- analysis is performed on studies which had ample data that comparatively analysed the efficiency of methylene blue. However, only two studies were selected for meta- analysis based on the availability of data.Systematic review reveals that methylene blue dye can be used as the best alternative when compared to other dyes in the detection of sentinel lymph node in the patients with breast cancer. However, the meta-analysis of two studies revealed no statistical significance defining the efficacy of methylene blue for sentinel lymph node detection.
ABSTRACT
Aims: To assess the psychological status of infertile women using the Fertility Problem Inventory and to identify any relationship between characteristics of infertility and the psychological problems.
Methods: A prospective, quantitative, descriptive, questionnaire- based study with institutional ethics committee clearance was conducted for two months, on women undergoing infertility treatment. Fertility Problem Inventory Questionnaire was applied and stress levels analyzed. Data were tabulated into Microsoft Excel and statistical analysis was performed in terms of percentages and students t tests for categorical variables.
Results: Thirty-two patients were studied in the time period with an average of 30.15 years. Seventy-five percent of the patients were found to be suffering from a moderately severe level of infertility-related stress. The remaining were suffering from a moderate level of infertility-related stress. The duration of marriage was found to have a significant correlation with the stress.
Conclusions: Majority (two-thirds) of the study group were suffering from a serious psychological morbidity. Psychological evaluation of people seeking infertility treatment could be considered
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