The DNA-containing Epstein-Barr herpesvirus has been implicated in the etiology of Burkitt's lymphoma, a malignant tumor of children in Africa. Recently, however, particles possessing four biochemical characteristics of RNA tumor viruses have also been identified in these tumors. The fact that both types of viruses are found suggests that an interaction between them niay be playing a role in the etiology of Burkitt The detection of viral-specific RNA in animal tumors by means of molecular hybridization (1) has been a useful tool in relating the etiology of these tumors to oncogenic RNA viruses (2, 3). Recently, radioactive DNA complementary to the RNA of the Rauscher murine leukemia virus was shown to hybridize with the RNA from murine and human leukemias (4), lymphomas (5), and sarcomas (6). Further, radioactive DNA complementary to the RNA of the mouse mammary tumor virus hybridized specifically with the RNA from murine mammary tumors (3) and from human malignant breast tumors (7).Burkitt's disease, a malignant lymphoma first described among African children, has been linked by means of seroepidemiology (8-10), electron microscopy (11), and molecular hybridization (12)

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