The hospital is a critical unit in the management process in general. This criticality becomes more pronounced when it comes to supply logistics. In the hospital unit, it is important to highlight the hospital pharmacy as an indispensable nucleus for effective and safe treatment of the patient. Objective: to identify and report the main difficulties and inefficiencies in the process of supply management in hospital pharmacies. Methodology: Literary review of articles indexed in lilacs, SPELL, Scielo, Medline and CAPES Journal Portal databases, from 2005 to 2019, on supply management in hospital pharmacies. Results: 25 articles were selected, which addressed the theme, which were critically studied, aiming to understand the supply chain process in hospital pharmacies. Conclusion: the main difficulty encountered was the effective control of inventories. As a result, at any given time, the lack of some materials and medications, thus bringing harm or damage to patients.