Kemuning (Murraya paniculata L) is a shrub growing in tropical climates and wildly in bushland or forest. The local people of Serawai ethnic in Bengkulu often use kemuning leaves as a traditional medicine for asthma disease. This research was a descriptive study by using interview method with purposive sampling techniques. Respondence samples of this study were five traditional medicine healer. This study aims to analyze the potential and benefits of Kemuning (Muraya paniculata L) leaves as a traditional medicine for asthma disease. The results found that the plant parts that are used as an asthma medicine that is the leaf organs by processing squeezed, filtered, smeared and drunk. Kemuning leaves have the potential to be developed as an asthma medicine, but further research needs to be conducted before used in pharmaceutical industry.