Ankylosing spondylitis (AS) is a chronic inammatory disease involving the axial skeleton and peripheral joints. It usually affects human leukocyte antigen-B27-positive individuals. Due to ossication of interspinous ligaments there is the formation of a bamboo-like spine. There is limitation of movement of neck when cervical spine is involved, thus making neck extension in general anaesthesia difcult. Involvement of the temporomandibular joint makes mouth opening difcult. Involvement of the cricoarytenoid joints makes oral intubation even more difcult.