In the present century an ever growing number of papers have been published describing the use of ionic liquids on organic synthesis. In general these works have shown evident advantages of this couple respect to conventional synthetic procedures for generation fast, efficient and environmental friendly synthetic methodologies. The industrial synthesis of pharmaceutical compounds often involves the use of organic solvents. Unfortunately, these reaction media are responsible for organic contaminations in the final product. In recent years, ionic liquids (ILs) have become the "green alternatives" of volatile organic solvents. Thus, the applications of ILs i nstead of con ve nti onal re a gents offer a new opportunity to solve problems of environmentally harmful solvents. This mini-review discusses a new application of ILs in laboratoryscale Pharmaceutical synthesis.

Since the beginning of the search of medicinally important synthetic compounds heterocyclic chemistry always remained the point of attraction because of their diverse biological properties. Compounds containing tetrazole moiety possess interesting biological activity. A series of tetrazole compounds were synthesized in order to obtain new compounds with potent antimicrobial, anti-inflammatory, anticancer, anticonvulsant, antibacterial activity etc. This review provides brief summary on the biological activities of various tetrazole derivatives that can helps in developing new tetrazole derivatives with better efficacy and more safety.