Demonetarization of currency notes of five hundred rupees and thousand rupees denominations is hailed because of surgical strike against black money, terrorist funding and also corruption. On the comparative lines the Government of India has introduced Jan Aushadhi scheme to give jolt to the uncontrolled medicine prices across all therapeutic category of medicines in India. Although brand medicines in India appear cheap when compared with international prices, however the brand medicines in India are expensive in comparison with generic medicines. The brand medicines despite being expensive are preferred over generic medicines by the prescribers due to exhaustive marketing practices by the manufactures. Although generic medicines are available at affordable prices they are not preferred over brand medicines. The price sensitivity for medicine appears to be very low. Generic medicines are less popular for various reasons, primarily due to marketing techniques of luring the prescribers brand medicines. The medicine prices are bound to get down to the ground levels when enactment of Jan Aushadhi Act is implemented in true spirit with a strong political will.

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The paradigm changes from the product-centric market to patient1 centric care are a revolutionary change in health care delivery. The Federation of International Pharmacy (FIP), WHO, and all most all drug regulatory authorities of the developed countries are emphasizing on the importance of patient centric care and outcome research to measure quality of life of the patients. The governments are encouraging the health care providers for focusing on the patient care by providing the direct incentivizes on the other hand, health insurance companies are also putting pressure on health care providers to minimize the cost on medication by adapting to generic prescribing. In developing 2 countries, although the government has realized the importance of patient centric care, they are also emphasizing to set the house in order by bringing various laws and regulations for example Pharmacy Practice Regulations 2015. In this manner they are bringing out fundamental changes in implementing the existing laws and enacting the new laws in regulations to improve the quality of life of patients. In this article we discuss the trends and their impact on clinical, humanistic and economic outcomes.

Background and Aim Medication use management involves a set of regulations and analytical techniques for defining comprehending and assessing medicine prescription distribution and consumption and also evaluating measures to improve the efficacy of these processes. The present study aimed to assess the medication use pattern prevalence and comorbidity conditions associated with cardiovascular diseases CVD.Methods A prospective observational study was conducted for a duration of six months in the inpatient medicine department of Chigateri District hospital Davangere Tertiary care teaching hospital. Two hundred four case reports of patients with CVD were reviewed and details such as demographics specified drugs prescribed Health Related Quality of Life HRQOL were recorded.Result Two hundred four patients were enrolled out of which 57.35 were males and 42.65 were females. Most of the patients were in the age range of 58-67 years. The most prevalent CVD treated was hypertension HTN 28.23 and the most common comorbidity associated was HTN 32.17. Social habits like smoking 13.75 and HTN 16.92 were found to be the most frequent associated risk factors in CVD patients. The most commonly prescribed class of drugs was antiplatelet 28.41 the common prescribed drug was Furosemide 13.39 and Fixed Dose Combination FDC was Ecosprin gold Atorvastatin Clopidogrel Aspirin 35.29. Most of the prescriptions showed polypharmacy 84.31. While assessing the HRQOL physical component summary PCS 56.94 and mental component summary MCS 54.24 were in a modest range.Conclusion The most prevalent type of CVD was HTN. HTN and DM were the prevalent comorbid conditions among the study population. In the study polypharmacy was noted which may have an impact on rationality. Statins and antiplatelet use was appropriate however excessive use of Furosemide must be controlled. Proper prescription writing increases patient treatment compliance which promotes reason.