quantifies the closeness among its neighbors. The centrality of the network is measured on the parameters, like eccentricity and CC, that define the maximum distance of a node to all other nodes. A node with lower eccentricity or higher CC is closer to the other nodes and more central. Each node in the network represents a protein and the edge denotes the dynamic interaction between the nodes (proteins). This molecular organization of all the differentially connected nodes is visualized as a network. The input and output values of the node are received as mathematical functions [28].