Organic reactions carried out in water under mild conditions are state‐of‐the‐art in terms of environmentally benign chemical processes. In this direction, plasmonic catalysis can aid in accomplishing such tasks. In the present work, cyclodextrin‐mediated AuPd bimetallic nanoparticles (NPs) were applied in room‐temperature aqueous Suzuki‐Miyaura reactions aiming at preparing biaryl products based on fluorene, isatin, benzimidazole and resorcinol, with yields of 77 % up to 95 %. AuPd NPs were revealed to be a physical mixture of Au and Pd particles circa 20 and 2 nm, respectively, through X‐ray diffraction, dynamic light scattering, UV‐Vis spectroscopy and transmission electron microscopy analyses.