Primary gastrointestinal melanomas (PGM) are usually asymptomatic in the early stages, leading to misdiagnosis. We reported the case of a 75-year-old male patient admitted to our service due to hematochezia, and fatigue. Primary investigation showed small bowel intussusception and surgical treatment was performed. Histopathology and immunohistochemistry analysis identified primary small bowel amelanotic melanoma at an advanced tumor stage. Whereas the patient had a sudden impairment of performance status during hospitalization, no curative oncological approach could be performed. This report highlights the clinical and imaging findings that led to the primary gastrointestinal amelanotic melanoma diagnosis in an elderly patient with intestinal intussusception. The early recognition of prior intussusception signs in adults and elder patients may lead to an earlier oncological diagnosis and a better prognosis.
Brazil is in fifth place among countries with the highest number of land transport accidents. The state of Paraná, Brazil, was the object of this study which conducted spatial analysis with the aim of identifying areas where this phenomenon occurs more and their time series over a 10-year period. This was an ecological and exploratory observational study covering the period 2007 to 2016 in 39 micro-regions of the state of Paraná. Data of road traffic accident deaths as per the International Classification of Diseases (ICD-10, codes V01 to V89) held on the Mortality Information System, were analyzed. Relative risk rates were calculated and choropleth maps were built. A total of 31,651 deaths from the causes examined were recorded according to municipality of occurrence. The most frequent ICD-10 items found were those involving automobile occupants, motorcyclists, pedestrians and cyclists in road traffic accidents. An overall falling trend was found with effect from 2012. The rate by area did not show pronounced spatial dependence and there was considerable variation, whereby the Cerro Azul micro-region had the lowest relative risk in the period, while in Campo Mourão deaths were around 53.3% above the expected level. The estimated average annual trend for the Curitiba micro-region had the steepest fall in the period, while Campo Mourão had the highest rising trend. The trend analysis indicated places where more robust public policy interventions and enforcement actions need to be reviewed.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
customersupport@researchsolutions.com
10624 S. Eastern Ave., Ste. A-614
Henderson, NV 89052, USA
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
Copyright © 2024 scite LLC. All rights reserved.
Made with 💙 for researchers
Part of the Research Solutions Family.