Introduction: HIV/AIDS Infection is one of the commonly encountered illness in our setup. It causes morbidity and mortality worldwide, and the number of HIV-infected patients has increased dramatically in the past decade. Current study aimed to record serum albumin level in patients suffering from HIV infection. Material and methods: A total of 175 subjects were studied over a period of 3 months. History and examination were done according to the proforma after taking written informed consent. Routine investigations included CD 4 Count and LFT. All data were entered in the master chart and analysed using SPSS Version 20 software Results: Out of 175 subjects majority were in age group of 41 to 50 years (30.4%) with mean age around 42 years and 101 subjects were males (57.7%). Low serum albumin was found in 67.2% of subjects. 12% of the subjects had CD 4 Count of less than 100 and among subjects with CD 4 Count of less than 100, 76% of the subjects had low serum albumin which was statistically significant with p value of 0.003. Conclusion: From the study can conclude that in HIV /AIDS patients serum albumin levels correlate with CD 4 counts and can be used as a marker of immune suppression.

No abstract

Background: Neuropeptide Y (NPY), a 36-AA neurotransmitter involved in the control of appetite, feeding and energy homeostasis. The bovine NPY gene is located on chromosome 4 and consists of four exons. Earlier studies have reported that genes involved in feed intake regulation, energy production and energy regulation may affect different growth and production traits in cattle. Information associating NPY SNP to reproduction and production traits in dairy cattle is, however, limited. Hence, the present study was planned to explore SNPs in NPY gene and its possible association with reproduction and first lactation production traits in Sahiwal cattle. Methodology: DNA samples were isolated from blood that has collected from hundred and three Sahiwal cows. Three regions of NPY were amplified using designed primer pairs. The sequencing of the targeted regions was done in 103 Sahiwal cows. Least squares analysis of variance was carried out for unequal and non-orthogonal data using the technique described by Harvey (1990) to study effect of non-genetic factors. Significance of differences based on genotypes effect of growth, reproduction and production traits were tested by general linear models. Result: Sequence data analysis revealed two transversions in NPY gene. For these identified nucleotide variations, positions were A72073973C (intron 3) and C72068620A (intron 3). This is the first report of the presence of NPY gene polymorphism in purebred Bos indicus of Indian origin. For SNP A72073973C, performances of animals with homozygote AA genotype exhibited significantly higher milk production (P≤0.01) and growth performance (P≤0.05) than heterozygote genotype. Heterozygous genotype exhibited superior performance for the SNP C72068620A which was found to be significantly associated (P£0.05) with 18M wt, WFS, WFC, FCI and FL305DMY.

No abstract

No abstract