Cows that received an over-calorie diet in the final phase of lactation are prone to liver lipidosis. The task of our research is to study the dynamics of cholesterol and triglycerides in cows with fatty hepatosis during the transit period. A group of 20 dry cows was formed. In the blood serum of cows, the concentration of cholesterol and triglycerides was studied twice before calving (15–20 days and 5–10 days) and twice after calving (5–10 days and 20–25 days). After research was formed two groups. The first group included 8 cows, which were killed 7–43 days after calving. They had signs of liver lipidosis. The diagnosis of fatty hepatosis was confirmed by the results of a histological examination of the liver. The second group included the remaining 12 cows. At the beginning of the study, the cows of the first and second groups had a cholesterol concentration of 4.06±0.23 and 3.62±0.23 mmol/l, and triglycerides - 0.13±0.01 and 0.11±0.01 mmol/l. Further dynamics of indicators had features in each group. In cows with hepatosis, a gradual decrease in cholesterol to 1.83±0.07 mmol/l was observed. In the second group the indicator was 2.2 times higher (P < 0.01). Before calving, a decrease in the concentration of triglycerides is observed. A more significant decline was detected in cows of the first group—by 61.5% (P < 0.001). In cows of the second group, the index decreased only by 18.2%. After 5–10 days after calving, the concentration of triglycerides in both groups remained low. After 20–25 days in the first group, the index increased 2.3 times (P < 0.01), and in the second—1.25 times. Studies have revealed features of the lipid profile in cows with liver lipidosis.
The relevance of the research topic is due to the strategic importance of the transition of Russian agro-industrial complex to innovative development path, which involves the formation of cooperative ties with the military-industrial complex as a driver of new technological solutions. Statement of the problem. The agro-industrial complex has a significant technological lag in terms of technological competitiveness. Statement of the problem. There is a significant technological gap in the agro-industrial complex in terms of smart growth of agribusiness based on digital technologies and solutions, which negatively affects its production, export potential and financial condition. The aim of the research is to study the development of inter-firm cooperation of military-industrial and agro-industrial complex of the Russian Federation which makes its influence on the environment. The study considers domestic and foreign experience in the implementation of inter-firm cooperation of industries, an analytical review of the main indicators of development and results of cooperation between the military-industrial complex and agro-industrial complex is given. The conclusion of the scientific research identifies the main problems and prospects for the development of cooperative links of industries, taking into account the external challenges and threats to the global economy.
Intestinal diseases of newborn calves, including enterocolitis, are the most common diseases of the digestive system of young cattle. Diseases, as a rule, develop from the first days of life of animals. The aim of the work was to study the dynamics of some indicators of the humoral immunity of newborn calves, as well as to assess the state of metabolism, taking into account the inclusion of probiotics and lipoic acid preparations in the treatment regimen for animals with enterocolitis. Sick animals of the first group (experimental I), in addition to the treatment provided for on the farm (diet therapy and antibiotic therapy), before feeding were asked inside 100 ml of probiotic starter culture based on the Enterococcus faecium L3 strain; to regulate lipid metabolism, a 0.5% solution of lipoic acid was administered intramuscularly at a dose of 2 ml once a day for 10 days. Sick animals of the second group (experimental II) were treated according to the scheme used in the farm. In calves of the I experimental group, in comparison with the animals of the II group, a significantly higher level of glucose, triglycerides and total protein in the blood was established. The amount of cholesterol was slightly higher compared to the initial level, but significantly lower than in the animals of the second experimental group. As a result of immunological studies, it was found that the indicators of nonspecific protection in sick calves of I and II experimental groups at 1-2 days of age had no significant differences. However, at the age of 10 days in calves, the studied parameters differed from each other BASK in the II experimental group was 42.7 ± 2.0% lysis, in animals of the I experimental group -50.4 ± 2.3% lysis (P <0.01), activity of beta-lysines 30.7±1.9%-lysis and 51.1±4.9%-lysis, respectively (P<0.01). Lysozyme activity of blood serum in calves of II and I experimental groups did not differ (P>0.05), and was at the level of 5.0±0.5%lysis and 5.2±0.9%-lysis, respectively. In the course of the studies, a positive effect of a probiotic based on the strain of microorganisms Enterococcus faecium L3 and 0.5% lipoic acid solution was established.
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