Here we report the one pot conversion of fructose to DFF in the presence of a mixture of choline chloride (ChCl) and DMSO as a solvent and Mo-Keggin heteropolyacids.Here we demonstrate that choline chloride has a beneficial effect on the direct conversion of fructose and inulin to DFF in the presence of Mo-V containing Keggin heteropolyacid. ChCl have two beneficial effects : 1) the enhancement of the conversion of fructose to HMF and 2) a higher conversion of HMF to DFF. A yield to DFF of 84% was obtained from fructose in the optimized conditions. In this mixture inulin was also converted to DFF.