The global variability of clouds and their interactions with aerosol and radiation make them one of our largest sources of uncertainty related to global radiative forcing. The droplet size distribution (DSD) of clouds is an excellent proxy that connects cloud microphysical properties with radiative impacts on our climate. However, traditional radiometric instruments are information-limited in their DSD retrievals. Radiometric sensors can infer droplet effective radius directly but not the distribution width, which is an important parameter tied to the growth of a cloud field and to the onset of precipitation. DSD heterogeneity hidden inside large pixels, a lack of angular information, and the absence of polarization limit the amount of information these retrievals can provide. Next-generation instruments that can measure at narrow resolutions with multiple view angles on the same pixel, a broad swath, and sensitivity to the intensity and polarization of light are best situated to retrieve DSDs at the pixel level and over a wide spatial field. The Airborne Hyper-Angular Rainbow Polarimeter (HARP) is a wide-field-ofview imaging polarimeter instrument designed by the University of Maryland, Baltimore County (UMBC), for retrievals of cloud droplet size distribution properties over a wide swath, at narrow resolution, and at up to 60 unique, colocated view zenith angles in the 670 nm channel. The cloud droplet effective radius (CDR) and variance (CDV) of a unimodal gamma size distribution are inferred simultaneously by matching measurement to Mie polarized phase functions. For all targets with appropriate geometry, a retrieval is possible, and unprecedented spatial maps of CDR and CDV are made for cloud fields that stretch both across the swath and along the entirety of a flight observation. During the NASA Lake Michigan Ozone Study (LMOS) aircraft campaign in May-June 2017, the Airborne HARP (AirHARP) instrument observed a heterogeneous stratocumulus cloud field along the solar principal plane. Our retrievals from this dataset show that cloud DSD heterogeneity can occur at the 200 m scale, much smaller than the 1-2 km resolution of most spaceborne sensors. This heterogeneity at the sub-pixel level can create artificial broadening of the DSD in retrievals made at resolutions on the order of 0.5 to 1 km. This study, which uses the AirHARP instrument and its data as a proxy for upcoming HARP CubeSat and HARP2 spaceborne instruments, demonstrates the viability of the HARP concept to make cloud measurements at scales of individual clouds, with global coverage, and in a low-cost, compact CubeSatsized payload.
Serial blast transformation in vitro was measured in peripheral lymphocytes from 38 patients with major thermal injury. Lymphocytes were tested with the antigens streptokinase-streptodornase (SKSD), mumps and purified protein derivative (PPD), the mitogens concanavalin A (Con A) and phytohemagglutinin (PHA), and in the one-way mixed lymphocyte reaction. Statistically significant suppression by the burn injury was noticed in all measurements except response to PHA. One-time measurements were not significantly different between the patients who survived and the patients who did not survive their burn injuries. However, serial determinations of responsiveness to the three natural antigens SKSD, mumps and PPD, as well as the mixed lymphocyte reaction accurately reflected prognosis.
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