The rate of ocular metastasis is even higher in postmortem studies since occult microscopic disease can be detected. In a postmortem study involving 230 patients, Bloch and Gartner7 found 23 cases (10%) to have metastases to the globe. In a prospective histopathological study of eyes from 716 subjects who had malignant neoplasms at the time of death, Nelson et a13 found ocular metastases in 52 (7 3%). They also observed that of 376 patients, dying of all types of carcinoma, 15 (4 0%) had ocular metastases. Of 512 patients with uveal metastases in the files of the Wills Eye Hospital, Shields et al 8 found that the iris was also involved in 40 (7-80/).As patients with metastatic malignancies live longer, ocular metastases will be detected more frequently.4 Although the prognosis of patients with ocular metastases is poor, if such lesions are detected early enough, they can be treated effectively with radiation therapy to improve vision and help maintain the quality of the patient's life.9 10 Intraocular metastases are the most common malignancy of the eye.7 11 12 We examined two groups of postmortem eyes (one by the dissecting microscope and the other histopathologically) to obtain information regarding the frequency of intraocular metastases in patients who have died of cancer.