This study was planned to evaluate the prokinetic effect of metoclopramide. For this purpose, 20 non-pregnant cattle were used and abomasal volume was assessed by ultrasonography. The abomasal volume was assessed 4 times every 2 hours and the first one was after feeding by 1hr. Two groups of cattle was used (10 of each), the first was as control and the second was received metoclopramide by intramuscular injection. The abomasal emptying rate/minute was estimated by dividing the degree of reduction of abomasal emptying volume every 2 hours(120 minute). The results revealed significant difference between control and that received metoclopramide . we could conclude that metoclopramide has prokinetic effect in cattle and could reflect good results on treatment of abomasal atony or other diseases causing abomasal emptying defect AED in cattle.