Continuous and advanced studies are necessary to explore and meet the continuous need of safe plant compounds necessary for pharmaceutical, therapeutic, food and other industries, especially special phytochemicals to be used as herbal and complementary medicine to combat various diseases and disorders. In this review, we highlight the uses of Ricinus communis in traditional medicine for treatment and others since ancient civilizations and its content of chemical compounds with multiple biological and therapeutic effects, including phenolic compounds, alkaloids, saponins, flavonoids, terpenes and oils and their uses as anti-cancer, antioxidant, anti-diabetic, anti-microbial, insecticide and anti-asthma Anti-ulcers, antimalarials, anti-inflammatories, hepatoprotective, bone regeneration, analgesics and anticonvulsants. It is worth noting that Ricinus communis grows in tropical and subtropical regions widely distributed throughout the world and the active substances are found in various parts of the plant, which necessitated that we focus the light on the plant and its multiple benefits and its rich effective compounds to further clinical, experimental and advanced studies to explore more and verify safety prospects.