Tumor puncture and spillage were the only variables that have an independent effect on recurrence, 26.9% of punctured tumors and 80% of cases of spillage recurred (P = .043 and P = .035, respectively). Although tumor size, safety margin, and adherence to facial nerve are related to recurrence, logistic regression suggests that these are confounding variables influencing recurrence through effect on puncture and spillage rates.
Because of CT's superiority in defining the bony margins and MRI's superior soft tissue resolution, CT and MRI should be used in a complementary manner in the evaluation of isolated sphenoid sinus disease in addition to mapping the lesion better and identifying intracranial and intraorbital extension. The use of one modality only should be restricted to straightforward lesions.
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