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Ellagic acid (EA) has demonstrated several biological properties, such as antioxidant, antimicrobial, and enzymatic inhibition. Zein and chitosan (CHI) are natural polymers whose biological potential has also gained attention. Therefore, this paper aimed to evaluate the antimicrobial, antioxidant, anticollagenase, and antielastase properties of EA, zein, and chitosan isolated or in combination. The microdilution method was used to assess the minimum inhibitory and bactericide concentrations. The antioxidant activity was determined using the 2,2-diphenyl-1-picryl-hydrazila free radical scavenging method. The anticollagenase and antielastase activities were evaluated by specific colorimetric tests. EA has shown inhibitory activity against Staphylococcus aureus and Pseudomonas aeruginosa together with an antioxidant IC 50 of 0.079 mg/mL. EA also showed significant collagenase and elastase inhibition. Zein has shown antimicrobial and antioxidant activities itself and enhanced sinergically the antioxidant activity and the antimicrobial activity against P. aeruginosa when combined with EA. CHI increased sinergically the inhibitory activity of EA against both bacterial strains, while showed itself an acceptable antimicrobial activity. 1 H saturation transfer-difference nuclear magnetic resonance experiment confirmed the formation of a complex between EA and zein that could be related with the improvement on its biological performance over the individual compounds, while no chemical interaction was detected between CHI and EA.Practical Application: The results reinforce the potential of ellagic acid in combination with zein and/or chitosan as an antimicrobial, antienzimatic, and antioxidant agent. Those findings reinforce the use of these substances, protecting this bioactive from degradation and/or improving the functional characteristics and biopharmaceutical properties.

RESUMOObjetivo: descrever a experiência do enfermeiro residente de enfermagem cirúrgica na elaboração de um instrumento de sistematização da assistência de enfermagem baseado na teoria das necessidades humanas básicas de Wanda Aguiar Horta. Métodos: trata-se de uma pesquisa descritiva, exploratória com abordagem qualitativa, do tipo relato de experiência realizada em hospital púbico. Resultados: criação de um instrumento que contempla todas as fases do processo de enfermagem baseado na teoria das necessidades humanas básicas, onde a assistência de enfermagem seria sistematizada e documentada e, assim, arquivada no prontuário do paciente. Conclusão: o instrumento elaborado é uma importante estratégia para a organização das ações e operacionalização do processo de enfermagem. Descritores: Assistência ao paciente; Teoria de enfermagem; Processo de enfermagem. ABSTRACTObjective: to describe resident nurse experience of surgical nursing in the elaboration of a nursing assistance systematization instrument based on Wanda Aguiar Horta's basic human needs theory. Methodology: This is a descriptive, exploratory research with a qualitative approach, of the type of experience report performed in a public hospital. Results: creation of an instrument that contemplates all phases of the nursing process based on basic human needs the theory, where nursing care would be systematized and documented and thus, stored in the patient's chart. Conclusion: the instrument developed is an important strategy for the actions organization and the nursing process operationalization. Descriptors: Patient care; Nursing theory; Nursing process. RESUMENObjetivo: describir la experiencia del enfermero residente de enfermería quirúrgica en la elaboración de un instrumento de sistematización de la asistencia de enfermería basado en la teoría de las necesidades humanas básicas de Wanda Aguiar Horta. Metodología: Se trata de una investigación descriptiva exploratoria con enfoque cualitativo, del tipo de informe de experiencia realizado en un hospital público. Resultados: creación de un instrumento que contemple todas las fases del proceso de enfermería basado en la teoría de las necesidades humanas básicas, donde la atención de enfermería sería sistematizada y documentada y, por lo tanto, almacenada en el cuadro del paciente. Conclusión: el instrumento desarrollado es una estrategia importante para la organización de acciones y operacionalización del proceso de enfermería. Descriptores: Atención al paciente; Teoría de enfermería; Proceso de enfermería. Relato de Experiência DIAGNÓSTICOS DE ENFERMAGEMNome:_______________________________________________Clínica:__________________________ Leito:______ 1 NECESSIDADES PSICOBIOLÓGICAS 1.1 -REGULAÇÃO NEUROLÓGICA 1 -Alteração no Processo de pensamento ( ) 2 -Memória prejudicada ( ) 3 -Confusão aguda ( ) Tavares FMM, Tavares WS. Revista de Enfermagem do Centro-Oeste Mineiro 2018; 8/2015 www.ufsj.edu.br/recom -5 4 -Negligência unilateral ( ) 1.2 -PERCEPÇÃO DOS ÓRGÃOS DOS SENTIDOS 1 -Alterações sensoriais percep...

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The use of chitosan biofilm in biomedical fields has a vast therapeutic potential due to useful properties such as biodegradability and antimicrobial activity, however, to achieve successful application some physicochemical properties need to be improved. In this context, the addition of glycerol to this biofilm is an alternative to improve its wettability and flexibility. Thus, low and high concentrations of plasticizer were added to this biomaterial for later characterization regarding its wettability, microstructure, mechanical and chemical properties. Glycerol addition to chitosan resulted in biofilms with more homogeneous surfaces, increased wettability, and increased flexibility, without significant changes in its chemical structure.