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Oral administration of 30 Gm. of activated charcoal to adult male volunteers 30 minutes after they had received 50 grains of aspirin resulted in a serum salicylate concentration 50 per cent of that of a control group. Vomiting induced by apomorphine also resulted in a similar difference. The use of both charcoal and induced emesis simultaneously caused a greater reduction in serum salicylate concentration than either measure alone.

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