benzoxazepines from the reaction of C-allylanilines and isothiocyanates or isocyanates without the need for the isolation of any intermediate is described. The compounds were obtained in good to moderate yields and some exhibited cytotoxic activity against tumor cell lines. Scheme 1 Synthesis of N-allylanilines 2a-d. Scheme 2 Synthesis of C-allylanilines 3a-d.
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