In order to enhance service provision to general public, information and communication technologies are increasingly being deployed in public sector around the globe, using a combination of processes, structures and relational mechanisms. The aim is to bring general public and governments close to each other. In these circumstances, it becomes important to elevate the technical threshold of the national economy as well as the intellectual capacity of the general public, so that all the stakeholders are at the same technical and procedural level of maturity. As a result, governments around the globe are embarking on technology enabled transformation programs that aim to revolutionize service delivery philosophy of public sector. However, for the success of these initiatives, it is important to assess how people view technology and how they respond to social, cultural, economic and behavioral changes brought about by technology. Different cultures around the globe respond differently to technology, therefore, road to etransformation in nations that are dubbed as 'melting pots of cultures' needs to be carefully planned and orchestrated. This paper contributes to the knowledge of how social and cultural issues impact on e-transformation. A literature review is conducted, exploring social and cultural issues in a number of geographical regions -The Far East, South East Asia, South Asia, Europe and Africa -and how e-transformation, in the forms of e-learning, e-commerce and e-government, is affected by them. This paper would be helpful for those researching factors which assist and inhibit e-transformation or technological change in general.