Owning to the requirements for longer endurance, larger payloads as well as simpler mechanical structure of tactical UAV, the two-element airfoil technology is introduced. Firstly, the aerodynamic characteristics of five common low-speed airfoils are calculated and compared. The airfoil with good aerodynamic performance after segmentation is selected as initial airfoil. Then, the influence of different segmentation types on the aerodynamic characteristics of airfoils is analyzed, and the segmentation type which brings the best aerodynamic benefits is selected. The slot parameters are optimized by NSGA-II optimization algorithm under cruising, take-off, and a large angle of attack states to obtain a high-performance self-adaption tactical UAV airfoil. Finally, the new airfoil is applied to Sparrow-hawk tactical UAV, the CL1.5 /CD of acceleration state increases 15.5%, the CL of large angle of attack increases 20.4% and the CL1.5 /CD of cruising state after enlarge the aspect ratio increase12.3%.