This study aimed to determine the prevalence, genotypic diversity, and antimicrobial resistance pattern of Salmonella isolated from meat goats in the Northeastern region of Thailand. A total of 1,014 rectal swabs were collected from 30 meat goat farms during April to November, 2018. Salmonella was isolated and identified according to the International Organization for Standardization protocol (ISO-6579:2002/AMD:2017) and serotyped using a slide agglutination test following the Kauffmann-White scheme. An antimicrobial susceptibility test to determine minimal inhibitory concentration (MIC) of 12 antimicrobial agents was performed using a broth microdilution method following the CLSI protocol (2017). Pulsed-field gel electrophoresis (PFGE) of XbaI digested chromosomal DNA was used to determine genotypic diversity of the isolates. The overall prevalence of Salmonella in the meat goats was 1.28%. A total of 13 Salmonella isolates recovered from the meat goats belonged to 4 serovars includings. Weltevreden (n=4), S. Bovismorbificans (n=4), S. Paratyphi B (n=4), and S. Stanley (n=1). Antimicrobial susceptibility testing revealed 2 antibiogram patternS. Eleven Salmonella isolates were susceptible to all antimicrobial agents tested, except sulfamethoxazole, and the other 2 isolates were susceptible to all antimicrobials. Genetic characterization of 13 Salmonella isolates by PFGE revealed 9 PFGE patterns that were grouped into 4 major clusters, A, B, C and D, with an 80% similarity value. This study revealed a low prevalence of Salmonella in meat goats in the Northeastern region of Thailand. Salmonella isolates were susceptible to most antimicrobials tested, with a very high proportion of resistance to sulfamethoxazole being observed.