A visible-light-induced highly selective alkylation and amination of unactivated C(sp 3 )-H bonds via the synergistic effects of an organo-photoredox catalyst and a bromine-based hydrogen atom transfer agent has been developed by applying CH 2 Br 2 as both the solvent and the bromine radical source. Our study offers a new paradigm for the direct synthesis of valuable compounds from abundant alkane feedstocks in a convenient and metal-free manner.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.