Metastatic pancreatic cancers are uncommon. The most common primary origins are renal, lung, breast, and colon cancer, with sarcoma and melanoma observed less commonly. Distinguishing a primary pancreatic cancer from a metastasis can be difficult based on various non-invasive imaging studies but is crucial to assure appropriate management. We reported a rare case of malignant uveal melanoma (UM) with metastatic recurrence to pancreas diagnosed by endoscopic ultrasound-guided (EUS) fine-needle aspiration (FNA). Under