A new tremulane sesquiterpene, ceriponol P, has been isolated from the cultures of Ceriporia lacerate, together with three known metabolites 3-indolecarbaldehyde, 3-methyl-2-indolinone, and daucosterol. Its structure was established by detailed analysis of its spectroscopic data, especially 1D, 2D NMR and HR-ESI-MS data. Ceriponol P represents the first example of monocyclic tremulane sesquiterpene. In biological assays, ceriponol P did not exhibit any significant cytotoxicity against HeLa, HepG2, and SGC 7901 cell lines at a concentration of 20 μM. All the known compounds were reported for the first time from the genus Ceriporia.
A new lycopodine alkaloid, 6α, 11α-dihydroxylycopodine, and three known compounds L20, lycoposerramine K, and huperzine A were isolated from the stems of Huperzia serrata. The structure of the new alkaloid was established by spectroscopic methods, especially two-dimensional NMR techniques.
Diels—Alder cycloadditions of arynes, in situ generated from 1,3‐diynes (I), and dienophiles, such as furans, cyclopentadiene, and pyrrole are developed.
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