A novel and efficient dual catalysis approach by concurrent activation of glycals and (o-azaaryl)-carboxaldehydes using palladium and N-heterocyclic carbene has been developed. The two electrophiles could react after activation through formation of the Breslow intermediate and a π-allyl Pd complex, widening the scope of reacting glycosylation partners and opening up possibilities for future glycosylation.

An efficient iron-catalyzed C-glycosylation method has been established. Starting from glycals and β-keto acids, a wide range of β-keto-functionalized 2,3-unsaturated C-glycosides have been synthesized in moderate to good yields with reasonable selectivities via decarboxylative Ferrier rearrangement reaction.

Polysubstituted indolizine derivatives are constructed via intramolecular CN bond formation/CH bond cleavage under metal-free conditions. These methods offer straightforward pathways to transform pyridyl chalcones into a variety of indolizines.

The first intermolecular interrupted imino-Nazarov reaction with silylated pyrimidine derivatives as nucleophile has been developed, furnishing carbocyclic nucleoside analogues in a one-pot operation.

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