In this study in patients with type 2 diabetes, near maximal glucose-lowering efficacy of sitagliptin after single oral doses was associated with inhibition of plasma DPP-4 activity of 80% or greater, corresponding to a plasma sitagliptin concentration of 100 nm or greater, and an augmentation of active GLP-1 and GIP levels of 2-fold or higher after an OGTT.

No abstract

MOF-derived ZnO@ZnO Quantum Dots/C core-shell nanorod arrays grown on flexible carbon cloth are successfully fabricated as a binder-free anode for Li-ion storage. In combination with the advantages from the ZnO/C core-shell architecture and the 3D nanorod arrays, this material satisfies both efficient ion and fast electron transport, and thus shows superior rate capability and excellent cycling stability.