The converter transformer plays a critical role in the high-voltage direct current (HVDC) transmission system, which connects but separates the AC grids and the converter. This paper briefly introduced the essential design requirement of the HVDC converter transformer in a system at ±800kV level and analyzed the DC bias influence on the transformer. The DC bias current effect simulations are analyzed in MATLAB and ANSYS Maxwell in this paper, respectively.

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A customized myopic refractive surgery was simulated by establishing a finite element model of the human eye,after which we studied the wavefront aberrations induced by biomechanical effects and ablation profile after wavefrontguided LASIK surgery.Methods: Thirty myopia patients (i.e., 60 eyes) without other eye diseases were selected. Their ages, preoperative spherical equivalent, astigmatism, and wavefront aberration were then obtained, in addition to the mean spherical equivalent error range -4 to -8D. Afterward, wavefront-guided customized LASIK surgery was simulated by establishing a finite element eye model, followed by the analysis of the wavefront aberrations induced by the surface displacement from corneal biomechanical effects, as well as customized ablation profile. Finally, the preoperative and induced aberrations were statistically analyzed.Results: Comatic aberrations were the main wavefront abnormality induced by biomechanical effects, and the wavefront aberrations induced by the ablation profile mainly included coma and secondary-coma, as well as sphere and secondarysphere aberrations. Overall, the total high-order aberrations (tHOAs), total coma (C 31 ), and sphere ( 0 4 C ) increased after wavefront-guided customized LASIK surgery. According to our correlation analyses, coma, sphere, and total high-order aberrations were significantly correlated with decentration. Additionally, the material parameters of ocular tissue were found to affect the postoperative wavefront aberrations. When the material parameters of the sclera remained constant but those of cornea increased, the induced wavefront aberrations were reduced. Conclusion:All biomechanical effects of cornea and ablation profile had significant effects on postoperative wavefront aberrations after customized LASIK refractive surgery; however, the effects of the ablation profile were more notorious.Additionally,the characteristics of biomechanical materials have influence on the clinical correction effect.

This paper explores how big data technology can be used for investment risk control in the financial industry. Through theoretical analysis, this paper expounds the application form and application effect of big data in financial investment risk control. Through the application analysis of risk control in banking and insurance industries in the financial field, this paper expounds the advantages of big data risk control, and expounds the data analysis process of big data risk control for reference.

Interferon-γ (IFN-γ) is a critical component of innate immune responses in humans to combat infection by many viruses, including human cytomegalovirus (HCMV). IFN-γ exerts its biological effects by inducing hundreds of IFN-stimulated genes (ISGs). In this study, RNA-seq analyses revealed that HCMV tegument protein UL23 could regulate the expression of many ISGs under IFN-γ treatment or HCMV infection. We further confirmed that among these IFN-γ stimulated genes, individual APOL1 (Apolipoprotein-L1), CMPK2 (Cytidine/uridine monophosphate kinase 2), and LGALS9 (Galectin-9) could inhibit HCMV replication. Moreover, these three proteins exhibited a synergistic effect on HCMV replication. UL23-deficient HCMV mutants induced higher expression of APOL1, CMPK2, and LGALS9, and exhibited lower viral titers in IFN-γ treated cells compared with parental viruses expressing full functional UL23. Thus, UL23 appears to resist the antiviral effect of IFN-γ by downregulating the expression of APOL1, CMPK2, and LGALS9. This study highlights the roles of HCMV UL23 in facilitating viral immune escape from IFN-γ responses by specifically downregulating these ISGs.