Universities, especially for technology transfer activities, always play the role of intermediaries in the innovation process. This study investigates three main issues related to open innovation based on bureaucratic perspective and scientific perspective. First, the protection power of technology is evaluated. Secondly, this study demonstrates determinants of successful technology transfer. Finally, this study examines the efficacy of technology transfer office in open innovation. Basing on literature reviews, we take the case study in Taiwan and try to make further insights for managing technology transfer in open innovation.

Circulating adhesion molecules (CAMs), surface proteins expressed in the vascular endothelium, have emerged as risk factors for cardiovascular disease (CVD). CAMs are involved in intercellular communication that are believed to play a role in atherosclerosis. A Chinese medicine, the “Dantonic Pill” (DP) (also known as the “Cardiotonic Pill”), containing three Chinese herbal material medica, Radix Salviae Miltiorrhizae, Radix Notoginseng and Borneolum Syntheticum, has been used in China for the prevention and management of CVD. Previous laboratory and animal studies have suggested that this preparation reduces both atherogenesis and adhesion molecule expression. A parallel double blind randomized placebo-controlled study was conducted to assess the effects of the DP on three species of CAM (intercellular cell adhesion molecule-1 (ICAM-1), vascular cell adhesion molecule-1 and endothelial cell selectin (E-selectin)) in participants with mild-moderate hypercholesterolemia. Secondary endpoints included biochemical and hematological variables and clinical effects. Forty participants were randomized to either treatment or control for 12 weeks. Treatment with DP was associated with a statistically significant decrease in ICAM-1 (9% decrease, P = .03) and E-Selectin (15% decrease, P = .004). There was no significant change in renal function tests, liver function tests, glucose, lipids or C-reactive protein levels and clinical adverse effects did not differ between the active and the control groups. There were no relevant changes in participants receiving placebo. These results suggest that this herbal medicine may contribute to the development of a novel approach to cardiovascular risk reduction.

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The principles of PWM and Hall sensor have been introduced in this paper. To the defects of traditional methods, it proposed the designing strategy of DC motor speed control system based on single chip microcontroller with integrated circuits, and described the overall framework of the system. The system will generate PWM signals to control the motor accelerating, decelerating and turning, its operating parameters can be obtained through the measurement module and displayed on LCD. Experiment proved that the system has high stability, and it can meet the needs of DC motor speed regulation.

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