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Gold nanorods conjugated with a hydrophilic photosensitizer, toluidine blue O, acted as dual-function agents in photodynamic inactivation and hyperthermia against methicillin-resistant Staphylococcus aureus.

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The best of three worlds: Gold nanorods coated with poly(styrene‐alt‐maleic acid) (see picture; pink), the photosensitizer indocyanine green (black), and antibodies (green “Y”) serve not only as photodynamic therapy and hyperthermia agents to destroy malignant cells, but they also act as optical contrast agents to simultaneously to monitor cells by imaging in the near‐IR region.