We design and fabricate a bilayer 3D scaffold inspired by the structure of skin. The top layer is made of silver loaded GelMA cryogel to prevent infection. The bottom layer is made of a PDGF-BB loaded 3D printed scaffold to promotes angiogenesis and collagen deposition to accelerate granulation tissue formation.

We developed an injectable hydrogel composed of amino-diethoxypropane modified alginate and chitosan, and also investigated bone marrow mesenchy + mal stromal cells (BMSCs) laden hydrogel for cartilage reconstruction in vitro and in vivo.