INTRODUCTION 1.1 | Clinical background Patients diagnosed with cancer may experience multiple symptoms, often co-occurring throughout their disease trajectory. Commonly reported symptoms include pain, fatigue, anxiety, lack of appetite, and lack of well-being 1-4 ; and a majority of patients experience both severe fatigue and lack of well-being in the initial months after diagnosis. 5 The prevalence and intensity of these symptoms varies by patient characteristics. Younger age, female sex, higher comorbidity burden, and lower income