Introduction: Chronic Rhinosinusitis (CRS) produce economic strain to patients and health system. The Sinonasal Outcome Test 22-item (SNOT-22) measured the subjective symptoms of CRS. This questionnaire was beneficial for clinical practice to understand the amplitude of patient's symptoms. While the objective measurement from CT-Scan was developed to evaluate the disease severity such as the Lund-Mackay Score (LMS) and the Harvard staging system. Objective: To examine the correlation between the SNOT-22 and the CT-Scan scoring system of Lund-Mackay Score and Harvard staging system in patients diagnosed with CRS. Material and Methods: This was a retrospective cross-sectional study using medical records between 1 January 2019 and 30 September 2021 in Otorhinolaryngology Head and Neck Surgery Department. A total of 29 patients were included in this study. The SNOT-22 score and CT-Scan were obtained as part of routine preparations before surgery and recorded in the medical records. Result:The correlation coefficient between the total score of SNOT-22 and LMS was 0.77 (p-value<0.05). There was a significant correlation between the total score of SNOT-22 and the Harvard staging (p-value <0.05). A significant correlation between SNOT-22 domain of rhinologic, sleep dysfunction, and psychological dysfunction domain with the Harvard staging system were found with the correlation coefficient of 0.57 (p-value <0.05), 0.44 (p-value = 0.02), 0.47 (p-value 0.01), respectively. Conclusions: In specific domains of SNOT-22, both CT-Scan scoring were correlated with the nasal domain. While only the Harvard staging system showing additional correlation with the sleep and psychological dysfunction domains.
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