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In the current study, seventy of patients were divided into three study groups: acute myocardial infarction (AMI) patients group included 21 subjects, unstable angina (UA) patients group included 23 subjects and stable angina (SA) patients group included 26 subjects, the control group was composed of 20 healthy. The samples were collected from the Coronary Care Unit (CCU) in Al-Sadder Teaching Hospital in Al-Najaf province/Iraq, during the period from September till December 2018. The ages of patients and control ranged from 30 to 69 years old, Each patients was divided into subgroups according gender, type of disease, and age.The current study indicated a significant increase (P<0.05) in serum VF level of CHD compared with healthy group. The results also revealed a significant increase (p<0.05) in serum V F the level in AMI group as compared with UA group and SA group. The current study indicated no significant differences (p>0.05) in serum level between males and females of CHD patients. The results also indicated when compared with (30-39y), (40-49y), (50-59y) and (60-69y ) of CHD, a significant increase (p<0.05) in serum level VF there was a significant increase (p<0.05) among different age.Conclusion: The present study concluded that Visfatin level were good marker for detection and diagnosis of coronary heart disease in male and female patients.

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