The case of an infant with neuroblastoma syndactyly and rib anomalies is presented. Twenty‐six cases of neuroblastoma have been recorded in which a variety of developmental defects have been found. The possible etiologic implications of the association of developmental defects with neuroblastoma are discussed. The absence generally of familial aggregation of neuroblastoma or of a specific pattern of associated developmental defects is consistent with the hypothesis that most cases of neuroblastoma result from sporadic postzygotic disorders. That germinal mutation may also rarely lead to neuroblastoma is suggested by the existence of four affected siblings in a single report.

Four men with clinical features of superior vena caval syndrome due to large substernal non-toxic multinodular goitre have undergone radionuclide superior vena caval studies. In all cases the dynamic scintigraphs showed a characteristic thyroidal configuration attributed to the definition of stretched thyroidal veins and their tributaries. Radiocontrast studies of two patients demonstrated the characteristic thyroid configuration. A radionuclide superior venacavogram taken post-thyroid lobectomy in one case showed the features had reverted to normal.

A case of thoracic sarcoidosis showing diffuse mediastinal lymphadenopathy was followed for a 6-month period with serial chest radiographs, perfusion lung scans, and pulmonary angiograms. Significant extrinsic pressure upon major pulmonary arteries from large lymph nodes of sarcoidosis was seen to cause marked restriction in pulmonary parenchymal perfusion on both scanning and angiography.

Seventy-four adults with documented deep-vein thrombosis of the pelvis and/or lower extremities had baseline and follow-up radionuclide venography (RNV), giving a total of 171 studies. Fifty-nine of the patients had unilateral venous thrombosis, of which 36 (61.0%) involved the left side and 23 (39.0%) the right. The higher incidence in the left side was attributed to the longer and more horizontal course of the left common iliac vein, as well as to compression by the right iliac artery and inguinal ligament. In 13 patients bilateral involvement was noted. "Normalisation" of the venous circulatory pattern was characterised by recanalisation and partial or significant disappearance of abnormal collaterals. This occurred in 43/74 patients. In 24 cases, no change was recorded during the interval, while seven patients deteriorated.