No abstract

The tetracycline analogs (TA) have been modified to contain boron. The new family of compounds provides a tool to reevaluate the over 40-year-old theory of thermal neutron, capture therapy for malignant cells.This report presents some tissue culture observations of the boron (TA) treated cells concerning intracellular incorporation and distribution. The synthesis of the boron TAs will be presented at a later date.

No abstract

Das Tetracyclinderivat (III) wird in einer Mannich‐Reaktion aus (I) und (II) synthetisiert,und seine spektroskopischen Eigenschaften sowie die Hydrolysestabilität werden untersucht.