Analysis 1.8. Comparison 1 Therapeutic hypothermia versus standard care: subgroup analysis by method of cooling, Outcome 8 Mental development (BSID MDI

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This systematic review provides high-quality evidence that delayed clamping reduced hospital mortality, which supports current guidelines recommending delayed clamping in preterm infants. This review does not evaluate cord milking, which may also be of benefit. Analyses of individual patient data in these and other randomized controlled trials will be critically important in reliably evaluating important secondary outcomes.

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