A method for the direct measurement of food intake in man is described. This method provides a means for independently studying many of the variables which are thought to operate in the control of food intake. A liquid diet from a hidden reservoir was ingested through a straw during a 20-min. breakfast or lunch meal. Subjects were tested at the same time each day for several weeks. Stable ingestion patterns emerged after four or five trials. The ingestion of a constant amount of liquid diet at various intervals before the test meal depressed intake as a function of the time interval. Subjective hunger ratings correlated well with rate and amount ingested and were reduced appropriately by ingestion prior to the test meal. R, .ECENT clinical studies of eating behavior in man have revealed a variety of disordered patterns, such as the nighteating and binge-eating syndromes of the obese, 15 and the often bizarre eating patterns in anorexia nervosa. 2 In addition, new experimental techniques used in the study of man have demonstrated

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Observed Pcrit provides a reliable descriptor of hypotonic upper airway collapsibility. Different methods for determining Pcrit were able to distinguish subjects with and without OSA.

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